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Holo-TC (Vitamin B12) Test

B12 status
The B12 level, which is usually measured in the blood also shows the amount of inactive B12. This value can provide an approximate guide, but it can also be misleading. A potential deficiency might be overlooked.

Holo-TC II (holotranscobalamin) value
A holo-transcobalamin II (holo-TC) test is recommended when examining the status of active B12 in the blood.


The Holo-TC value is measured in the capillary blood. To do this, a little blood is drawn from the fingertip. The sample is analyzed in the laboratory and after a few days the result is available. A short consultation is included in the price of 48 €.


B12 - important for many metabolic functions in the body

  • DNA synthesis

  • Breakdown of fatty acids

  • Blood formation

  • Keeping the nervous system healthy

  • Cell division


Occurrence in food
Vitamin B12 is produced by microorganisms. B12-producing bacteria are found in the intestines of some animals, as well as in the soil and contaminated water. Relevant amounts of B12 are only found in foods of animal origin such as meat, milk or eggs. Certain plant-based foods such as algae (spirulina) or sauerkraut contain either vitamin B12 analogues (inactive forms), very small amounts, or strongly varying amounts of B12.


Vegans, vegetarians and omnivores over 50 

With a vegan diet, vitamin B12 must be supplemented. Vegetarians are also often affected by an undersupply. People over 50 are also advised to keep an eye on their blood B12 status. The metabolism of B12 becomes more difficult with increasing age due to problems of proportion.


B12 deficiency
Early symptoms: disruption of cell division in the bone marrow

Late symptoms: pernicious anemia, funicolary myelosis


B12 deficiency can cause irreversible damage to the nerves and spinal cord.


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